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Optimizing the Treatment of Complicated Grief

Description:
The purpose of this research study is to find out how effective the SSRI antidepressant, citalopram (CIT), is administered over a 16 week period with or without a targeted psychotherapy called Complicated Grief Therapy (CGT). Aftern medical and psychiatric evaluations are completed, eligible subjects are randomly assigned to (that is, by chance) to one of 4 study treatments (with a 1 in 4 chance of being assigned to each group):
  • Complicated Grief Therapy (CGT) plus antidepressant medication (citalopram)
  • CGT plus placebo (a pill without active medication)
  • Medication (citalopram) without CGT
  • Placebo without CGT

Key Eligibility Criteria

  • Individuals 18 years or older with a primary diagnosis of Complicated Grief (as determined by the psychiatrists who conduct our initial screening process).
  • Physical examination and laboratory findings without clinically significant medical problems.
  • Pregnant or lactating women or those able to become pregnant not using medically accepted forms of birth control cannot take part in the research study.


 
If you are interested in participating:
  • Call the Center for Anxiety and Traumatic Stress Disorders:              1 (866) 44-WORRY 
  • Or send an email to: anxietystudy@partners.org

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Center for Anxiety and Traumatic Stress Disorders
Massachusetts General Hospital
1 Bowdoin Square, Boston MA 02114