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Optimizing the Treatment of Complicated Grief

Description:
The purpose of this research study is to find out how effective the SSRI antidepressant, citalopram (CIT), is administered over a 16 week period with or without a targeted psychotherapy called Complicated Grief Therapy (CGT). After medical and psychiatric evaluations are completed, eligible subjects are randomly assigned (that is, by chance) to one of 4 study treatments (with a 1 in 4 chance of being assigned to each group):
  • Complicated Grief Therapy (CGT) plus antidepressant medication (citalopram)
  • CGT plus placebo (a pill without active medication)
  • Medication (citalopram) without CGT
  • Placebo without CGT

Key Eligibility Criteria

  • Individuals 18 years or older with a primary diagnosis of Complicated Grief (as determined by the psychiatrists who conduct our initial screening process).
  • Physical examination and laboratory findings without clinically significant medical problems.
  • Pregnant or lactating women or those able to become pregnant not using medically accepted forms of birth control cannot take part in the research study.


 
If you are interested in participating:
  • Call the Center for Anxiety and Traumatic Stress Disorders:              1 (866) 44-WORRY 
  • Or send an email to: anxietystudy@partners.org

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Partner Treatment Sites in New York, Pittsburg, and San Diego
  
New York, New York 
Katherine Shear, MD
HEAL Study Principal Investigator; Director, The Complicated Grief Program, Columbia University School of Social Work.
Rachel Fox, MS
Clinical Coordinator, The Complicated Grief Program, Columbia University School of Social Work.
Phone: 212-851-2107

raf2130@columbia.edu

Pittsburg Pennslyvania
Charles F. Reynolds III, MD
HEAL Study Principal Investigator; Professor of Geriatric Psychiatry, University of Pittsburgh School of Medicine; Professor of Behavioral and Community Health Sciences, University of Pittsburgh Graduate School of Public Health
Jill Houle, BSE
Program Coordinator, University of Pittsburgh Medical Center
Phone: 412-246-6006

houldja@upmc.edu

www.healstudy.org

  
San Diego, California
Sidney Zisook, MD
HEAL Study Principal Investigator; Professor of Psychiatry, VA San Diego Healthcare System and University of California, San Diego
Ilanit Tal Young, PhD
HEAL Study Research Coordinator, Veterans Medical Research Foundation
Phone: 858-552-7598

ityoung@vapop.ucsd.edu
 

 

Center for Anxiety and Traumatic Stress Disorders
Massachusetts General Hospital
1 Bowdoin Square, Boston MA 02114